I’ve done this a few times already, and it seems every time I make the same time-wasting mistakes. So here’s the process quick and dirty (be sure to follow the links if there’s a point you don’t understand or know how to do):
If you’ve never used Zend Framework before, you may want to follow along with the Quickstart from here.
If you’re going to using Flash, make sure to make the change in the .htaccess I mention here. Also, if you plan on uploading images at some point and would like MIME type validation and/or file information you’ll need to install the PECL fileinfo extension as explained by Jeffrey Barke on his website.
That’s it. Kind of a pain since you have to do this every time you set up a new site (domain or subdomain), granted you could probably put the framework higher in the operating system and just link to it, but that has it’s own problems (i.e. framework version support/maintenance) and it wouldn’t save you any steps. Anyway, hope this is as useful to someone else as I know it will be to me.